Friday, April 26, 2013

'Taxels' convert mechanical motion to electronic signals

Apr. 25, 2013 ? Using bundles of vertical zinc oxide nanowires, researchers have fabricated arrays of piezotronic transistors capable of converting mechanical motion directly into electronic controlling signals. The arrays could help give robots a more adaptive sense of touch, provide better security in handwritten signatures and offer new ways for humans to interact with electronic devices.

The arrays include more than 8,000 functioning piezotronic transistors, each of which can independently produce an electronic controlling signal when placed under mechanical strain. These touch-sensitive transistors -- dubbed "taxels" -- could provide significant improvements in resolution, sensitivity and active/adaptive operations compared to existing techniques for tactile sensing. Their sensitivity is comparable to that of a human fingertip.

The vertically-aligned taxels operate with two-terminal transistors. Instead of a third gate terminal used by conventional transistors to control the flow of current passing through them, taxels control the current with a technique called "strain-gating." Strain-gating based on the piezotronic effect uses the electrical charges generated at the Schottky contact interface by the piezoelectric effect when the nanowires are placed under strain by the application of mechanical force.

The research will be reported on April 25 in the journal Science online, at the Science Express website, and will be published in a later version of the print journal Science. The research has been sponsored by the Defense Advanced Research Projects Agency (DARPA), the National Science Foundation (NSF), the U.S. Air Force (USAF), the U.S. Department of Energy (DOE) and the Knowledge Innovation Program of the Chinese Academy of Sciences.

"Any mechanical motion, such as the movement of arms or the fingers of a robot, could be translated to control signals," explained Zhong Lin Wang, a Regents' professor and Hightower Chair in the School of Materials Science and Engineering at the Georgia Institute of Technology. "This could make artificial skin smarter and more like the human skin. It would allow the skin to feel activity on the surface."

Mimicking the sense of touch electronically has been challenging, and is now done by measuring changes in resistance prompted by mechanical touch. The devices developed by the Georgia Tech researchers rely on a different physical phenomenon -- tiny polarization charges formed when piezoelectric materials such as zinc oxide are moved or placed under strain. In the piezotronic transistors, the piezoelectric charges control the flow of current through the wires just as gate voltages do in conventional three-terminal transistors.

The technique only works in materials that have both piezoelectric and semiconducting properties. These properties are seen in nanowires and thin films created from the wurtzite and zinc blend families of materials, which includes zinc oxide, gallium nitride and cadmium sulfide.

In their laboratory, Wang and his co-authors -- postdoctoral fellow Wenzhuo Wu and graduate research assistant Xiaonan Wen -- fabricated arrays of 92 by 92 transistors. The researchers used a chemical growth technique at approximately 85 to 90 degrees Celsius, which allowed them to fabricate arrays of strain-gated vertical piezotronic transistors on substrates that are suitable for microelectronics applications. The transistors are made up of bundles of approximately 1,500 individual nanowires, each nanowire between 500 and 600 nanometers in diameter.

In the array devices, the active strain-gated vertical piezotronic transistors are sandwiched between top and bottom electrodes made of indium tin oxide aligned in orthogonal cross-bar configurations. A thin layer of gold is deposited between the top and bottom surfaces of the zinc oxide nanowires and the top and bottom electrodes, forming Schottky contacts. A thin layer of the polymer Parylene is then coated onto the device as a moisture and corrosion barrier.

The array density is 234 pixels per inch, the resolution is better than 100 microns, and the sensors are capable of detecting pressure changes as low as 10 kilopascals -- resolution comparable to that of the human skin, Wang said. The Georgia Tech researchers fabricated several hundred of the arrays during a research project that lasted nearly three years. The arrays are transparent, which could allow them to be used on touch-pads or other devices for fingerprinting. They are also flexible and foldable, expanding the range of potential uses.

Among the potential applications:

? Multidimensional signature recording, in which not only the graphics of the signature would be included, but also the pressure exerted at each location during the creation of the signature, and the speed at which the signature is created.

? Shape-adaptive sensing in which a change in the shape of the device is measured. This would be useful in applications such as artificial/prosthetic skin, smart biomedical treatments and intelligent robotics in which the arrays would sense what was in contact with them.

? Active tactile sensing in which the physiological operations of mechanoreceptors of biological entities such as hair follicles or the hairs in the cochlea are emulated. Because the arrays would be used in real-world applications, the researchers evaluated their durability. The devices still operated after 24 hours immersed in both saline and distilled water.

Future work will include producing the taxel arrays from single nanowires instead of bundles, and integrating the arrays onto CMOS silicon devices. Using single wires could improve the sensitivity of the arrays by at least three orders of magnitude, Wang said. "This is a fundamentally new technology that allows us to control electronic devices directly using mechanical agitation," Wang added. "This could be used in a broad range of areas, including robotics, MEMS, human-computer interfaces and other areas that involve mechanical deformation."

This research was supported by the Defense Advanced Research Projects Agency (DARPA), the National Science Foundation (NSF) under grant CMMI-0946418, the U.S. Air Force (USAF) under grant FA2386-10-1-4070, the U.S. Department of Energy (DOE) Office of Basic Energy Sciences under award DE-FG02-07ER46394 and the Knowledge Innovation Program of the Chinese Academy of Sciences under grant KJCX2-YW-M13. The content is solely the responsibility of the authors and does not necessarily represent the official views of DARPA, the NSF, the USAF or the DOE.

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The above story is reprinted from materials provided by Georgia Institute of Technology, Research Communications, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Wenzhuo Wu, Xiaonan Wen, Zhong Lin Wang. Taxel-addressable matrix of vertical-nanowire piezotronic transistors for active/adaptive tactile imaging. Science, 2013 DOI: 10.1126/science.1234855

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/electronics/~3/-jrj0Z-Yh-E/130425142247.htm

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Utah Teacher Accused of Raping Female Student

Source: http://www.thehollywoodgossip.com/2013/04/utah-teacher-accused-of-raping-female-student/

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Autism risk spotted at birth in abnormal placentas

Apr. 25, 2013 ? Researchers at the Yale School of Medicine have figured out how to measure an infant's risk of developing autism by looking for abnormalities in his/her placenta at birth, allowing for earlier diagnosis and treatment for the developmental disorder. The findings are reported in the April 25 online issue of Biological Psychiatry.

One out of 50 children are diagnosed with an autism spectrum disorder in the United States each year, according to the Centers for Disease Control and Prevention (CDC), but the diagnosis is usually made when these children are 3 to 4 years of age or older. By then the best opportunities for intervention have been lost because the brain is most responsive to treatment in the first year of life.

Senior author Dr. Harvey Kliman, research scientist in the Department of Obstetrics, Gynecology & Reproductive Sciences at the Yale School of Medicine, and research collaborators at the MIND Institute at the University of California, Davis, have found that abnormal placental folds and abnormal cell growths called trophoblast inclusions are key markers to identify newborns who are at risk for autism.

Kliman and his team examined 117 placentas from infants of at-risk families, those with one or more previous children with autism. These families were participating in a study called Markers of Autism Risk in Babies -- Learning Early Signs. Kliman compared these at-risk placentas to 100 control placentas collected by the UC Davis researchers from the same geographic area.

The at-risk placentas had as many as 15 trophoblast inclusions, while none of the control placentas had more than two trophoblast inclusions. Kliman said a placenta with four or more trophoblast inclusions conservatively predicts an infant with a 96.7% probability of being at risk for autism.

Currently, the best early marker of autism risk is family history. Couples with a child with autism are nine times more likely to have another child with autism. Kliman said that when these at-risk families have subsequent children they could employ early intervention strategies to improve outcomes. "Regrettably couples without known genetic susceptibility must rely on identification of early signs or indicators that may not overtly manifest until the child's second or third year of life," said Kliman.

"I hope that diagnosing the risk of developing autism by examining the placenta at birth will become routine, and that the children who are shown to have increased numbers of trophoblast inclusions will have early interventions and an improved quality of life as a result of this test," Kliman added.

Other authors on the study include Kaitlin Anderson, Kristin Milano, and Saier Ye of Yale University; and Cheryl Walker, Daniel Tancredi, Isaac Pessah, and Irva Hertz-Picciotto of UC Davis.

This work was supported by the National Institutes of Health (1 P01 ES11269 and R01 ES 015359), the U.S. Environmental Protection Agency through the Science to Achieve Results (STAR) program (R829388 and R833292), the MIND Institute at the University of California, Davis, and the Yale University Reproductive and Placental Research Unit.

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The above story is reprinted from materials provided by Yale University. The original article was written by Karen N. Peart.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Cheryl K. Walkera, Kaitlin W. Andersong, Kristin M. Milanoh, Saier Yei, Daniel J. Tancredie, Isaac N. Pessahc, Irva Hertz-Picciottob, Harvey J. Klimang. Trophoblast Inclusions Are Significantly Increased in the Placentas of Children in Families at Risk for Autism. Biological Psychiatry, 2013 DOI: 10.1016/j.biopsych.2013.03.006

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/7OtN05U-7iQ/130425091604.htm

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Thursday, April 25, 2013

Dental records of missing Brown student requested after body found in river

?

By Dan Stamm, NBCPhiladelphia.com

The family of missing Brown University student Sunil Tripathi has been asked to provide dental records to the medical examiner in Providence, R.I.

The ME?is trying to identify the body of a man that was pulled from the Providence River late Tuesday afternoon. According to the lead investigator on the case, the ME expects to release the identity of the victim either Thursday or Friday.

Tripathi, 22, who is from Bryn Mawr, Pa., has been missing since March 16.?He was last seen on surveillance video early that morning, not far from his apartment on Brook Street, near campus.

The body was found by members of the school's crew team in the water near India Point Park, which is a few blocks away from Tripathi's apartment. Police on the scene said the body appeared to be that of a man in his 20s.

When reached by phone, Tripathi's brother Ravi told NBC10's Monique Braxton that the family is in Providence?and aware of the report. They?don't plan on commenting until the ME has determined the identity.

Tripathi, a graduate of Radnor High School, moved to Providence?to attend Brown. He was studying philosophy but took a leave this semester. Sunil battles depression and was working through a "tough time," his sister Sangeeta said last month. The family felt that in the weeks before he disappeared, however, Sunil was doing well.?

On the day his brother went missing, Ravi Tripathi made the trip from Philadelphia to Providence as fast as he could.

?We dropped everything. We didn?t even pack. And then a couple of days turned into over a month.?

Since then -- 38 days now -- Providence has been ground zero in the search for Sunil Tripathi. His immediate family, extended family and close friends are all there together. Every day they meet and collaborate on what they can do next.

Last week Sunil's case was thrust back into the spotlight following?a viral onslaught of erroneous speculation that Tripathi was connected to the Boston Marathon bombings.

"It's a very scary thing to be on the other side of it and see how quickly our voices got drowned out and hysteria took over,"?Ravi Tripathi said in an interview on Monday.

The Tripathi family has been posting the latest information and messages of hope on their ?Help Us Find Sunil Tripathi? Facebook page.

"It's been a roller coaster for all of us," Ravi said earlier this week, reflecting back on the five weeks they've spent searching for Sunil.? Ravi said he would always be grateful for the time everyone has spent together, saying the support of family and friends has been "beautiful. A gift."

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Video: Scientists advance understanding of human brown adipose tissue and grow new cells

Video: Scientists advance understanding of human brown adipose tissue and grow new cells

Tuesday, April 23, 2013

Joslin scientists report significant findings about the location, genetic expression and function of human brown adipose tissue (BAT) and the generation of new BAT cells. These findings, which appear in the April 2013 issue of Nature Medicine, may contribute to further study of BAT's role in human metabolism and developing treatments that use BAT to promote weight loss.

Two types of adipose (fat) tissue ? brown and white -- are found in mammals. Unlike the more predominant white adipose tissue (WAT) which stores fat, BAT burns fat to produce heat when the body is exposed to cold and also plays a role in energy metabolism. Human studies have shown that greater quantities of BAT are associated with lower body weight. BAT has been a major focus of study among scientists and pharmaceutical companies based on its potential as a treatment to combat obesity, a major risk factor for type 2 diabetes.

Studies in mice have identified two types of BAT: constitutive or "classical" BAT which is present at birth and persists throughout life and recruitable or "beige" BAT which can be produced from within white fat in response to metabolic conditions. These two types of BAT may also be present in humans.

Previous studies have identified the human neck as a primary location for BAT deposits. To determine the precise locations of these deposits, Joslin scientists obtained fat samples from five neck regions of patients undergoing neck surgery. Analysis of the samples showed that BAT was most abundant in deep regions of the neck, near the carotid sheath and longus colli muscles. These samples expressed the BAT marker gene, uncoupling protein 1 (UCP1), which is involved in heat generation. "BAT is most abundant in the deep locations of the neck, close to the sympathetic chain and the carotid arteries, where it likely helps to warm blood and raise body temperature. Now that we know where brown fat is, we can easily collect more cells for further study," says Aaron M. Cypess, M.D., Ph.D., senior author and Assistant Investigator in the Section of Integrative Physiology and Metabolism and Assistant Professor at Harvard Medical School.

In analyzing genetic expression in superficial and deep human neck fat tissue, the fat from deep locations was found to most closely resemble cells from constitutive mouse BAT, the kind already known to consume large quantities of glucose and fat.

The Joslin scientists compared the oxygen consumption rate (OCR), which demonstrates the capacity to burn calories, of human BAT cells to mouse constitutive BAT cells and human WAT. This is the first study to directly measure brown fat cells' OCR at baseline. The OCR of the human BAT cells from the deep location next to the longus colli was nearly 50 percent of the mouse BAT cells; in contrast, the OCR of human WAT was only one-hundredth of the OCR found in the most active human BAT from the longus colli depot. "We show that at baseline, brown fat cells have a great capacity to burn fat," says Dr. Cypess.


Joslin scientists report significant findings about the location, genetic expression and function of human brown adipose tissue (BAT) and the generation of new BAT cells. These findings, which appear in the April 2013 issue of Nature Medicine, may contribute to further study of BAT's role in human metabolism and developing treatments that use BAT to promote weight loss. Credit: Joslin Communications

The scientists were able to grow new functional brown fat cells (adipocytes) by differentiating precursor cells (preadipocytes) derived from both superficial and deep human neck fat tissue. When stimulated, the cells expressed the same genes as naturally occurring brown fat cells. This is the first report of the production of brown fat cells (adipogenesis) that can respond to pharmacological stimulation.

The Joslin scientists are following up on this study to learn more about the functions of BAT, including how it affects energy balance and uses glucose. Having the ability to produce brown fat cells outside the body will make it possible to develop drugs and other potential treatments that increase BAT activity to combat obesity. "Our research has significant practical applications. If we stimulate the growth of brown fat in people, it may burn their white fat and help them lose weight, which lessens insulin resistance and improves diabetes," says Dr. Cypess.

###

Joslin Diabetes Center: http://www.joslin.org

Thanks to Joslin Diabetes Center for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127868/Video__Scientists_advance_understanding_of_human_brown_adipose_tissue_and_grow_new_cells

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Wednesday, April 24, 2013

Senate DFLers want to raise income taxes for wider group, tax clothing (Star Tribune)

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CA-BUSINESS Summary

TSX slips as gold, energy shares drag

TORONTO (Reuters) - Canada's main stock index turned lower in early Tuesday trade, with weakness in commodity prices weighing on shares of gold and energy companies, as weak economic data from China and Germany dampened investor sentiment. The Toronto Stock Exchange's S&P/TSX composite index <.gsptse> was down 22.83 points, or 0.19 percent, at 12,067.85, after opening higher.

Manufacturing data stokes fears of global spring swoon

NEW YORK/LONDON (Reuters) - Major economies in North America, Europe and Asia lost some momentum this month, a clutch of business surveys showed on Tuesday, raising concerns about the strength of the global recovery. China and Germany, the world's biggest exporters, both lost momentum in April. Growth in Chinese factories slowed to a crawl as export demand dwindled, while the euro zone's largest economy saw business activity decline for the first time in five months.

Canadian February retail sales rise more than expected

OTTAWA (Reuters) - Canadian retail sales in February rose a greater-than-expected 0.8 percent from January, pushed up by higher sales at general merchandise stores and gas stations, Statistics Canada data indicated on Tuesday. The increase was greater than the 0.3 percent advance predicted by market operators. Statscan trimmed January's growth to 0.9 percent, from an initial 1.0 percent.

NTSB looks for cause, larger lessons in Boeing 787 battery fire

WASHINGTON (Reuters) - The top U.S. transportation safety regulator is looking beyond what caused a Boeing Co Dreamliner battery to fail in January at larger lessons that can be applied to the airplane certification process and new technologies. A two-day hearing at the National Transportation Safety Board headquarters in Washington that began on Tuesday is part of the agency's investigation into what caused a battery to catch fire and burn on a parked 787 Dreamliner in Boston in January. The battery fire occurred after passengers had deplaned, and workers noticed smoke in the cabin. It took firefighters more than an hour to put the fire out.

Bank of Canada repeats language on higher interest rates

OTTAWA (Reuters) - Outgoing Bank of Canada Governor Mark Carney on Tuesday repeated the central bank's warning that it expects its next move to be an interest rate increase, even after recently cutting growth forecasts. "The considerable monetary policy stimulus currently in place will likely remain appropriate for a period of time, after which some modest withdrawal will likely be required, consistent with achieving the 2 per cent inflation target," he told a Canadian parliamentary committee.

Global survey reveals unhappiness with retail banks

LONDON (Reuters) - Banks have made little progress in improving customer service over the past year, with around a half of their retail customers considering switching to a rival, according to a survey published on Tuesday. The 2013 World Retail Banking Report from Capgemini , which polls over 18,000 retail banking customers in 35 countries, found that 41 percent of customers were unsure if they would stay with their bank in the next six months, while an additional 10 percent indicated that they would leave.

TransAlta posts loss on pension funding

(Reuters) - Canadian power generation company TransAlta Corp reported a first-quarter loss, hurt in part by a one-time charge related to pension funding obligations. The company posted a loss of C$11 million, or 4 Canadian cents per share, in the first quarter, compared with a profit of C$88 million, or 39 Canadian cents per share, a year earlier.

Encana operating profit falls on hedging losses

(Reuters) - EnCana Corp , Canada's No.1 natural gas producer, reported a 25 percent fall in first-quarter operating profit due to hedging losses. Encana's net operating income, which excludes most one-time items, fell to $179 million, or 24 cents per share, in the first quarter, from $240 million, or 33 cents per share, a year earlier.

Euro zone slump moderates but German worries appear: PMIs

LONDON (Reuters) - A sharp drop in German business activity overshadowed an easing downturn in France in April, surveys showed on Tuesday, raising concerns over a further economic contraction in the euro zone. Markit's flash euro zone services PMI, an early gauge of business activity each month, rose to 46.6 in April from 46.4 in March, below the 50 line that divides growth from contraction but matching the forecast of economists.

Xerox steps up restructuring, second-quarter EPS goal below Street

(Reuters) - Xerox Corp on Tuesday forecast second-quarter earnings below estimates as it accelerates its restructuring efforts to become a broader technology company. In an attempt to counter sluggish growth in its technology business, which includes printers and copiers, Xerox has been transforming itself into a business services provider, offering services such as managing toll systems and healthcare programs.

Source: http://news.yahoo.com/ca-business-summary-114755430.html

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